Sulfuric Acid → HCID 86639892、化合物

HRID 39209ノート

反応式

HRID 39209 の反応式
[CH3:1][N:2]([CH3:11])[C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][C:5]([OH:7])=[O:6].[S:12](=[O:16])(=[O:15])([OH:14])[OH:13]>O>[S:12]([OH:16])([OH:15])(=[O:14])=[O:13].[CH3:11][N:2]([CH3:1])[C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][C:5]([OH:7])=[O:6]

参加物

4

反応物 2

HCID 1118Sulfuric AcidHCID 12774059Dimethyl aspartic acid

生成物 1

HCID 86639892HCID 86639892、化合物収率 95.4%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

10 g of dimethylaspartic acid was placed in a 250 ml round-bottom flask, and 40 ml of water was added and stirred for 30 minutes. Then, 7.36 g of concentrated sulfuric acid (concentration: 98%) was slowly added to the flask. After the addition, a reaction was conducted for 2 hours. The reaction solution was concentrated, and azeotroped with 100 ml of toluene to further remove the water. Afterwards, the product was dried under high vacuum, and ground by using a spatula to obtain 15.34 g of N,N-dimethylaspartic acid sulfate as tawny oil (Yield: 95.33%).

後処理

  1. additionAfter the addition
  2. waita reaction was conducted for 2 hours
  3. concentrationThe reaction solution was concentrated
  4. customazeotroped with 100 ml of toluene
  5. customto further remove the water
  6. customAfterwards, the product was dried under high vacuum, and ground

出典と根拠

ORDレコード
ord-1b3390e9bfa64341bea863de1043ac68
出典データセット
uspto-grants-2013_09
特許番号
US08524895B2

反応ノート

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