化工社化工社 化学情報印刷レポート · 研究参考用
Ethanol → HCID 22663744、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | 6-fluoro-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-one | HCID 11063293 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | HCID 178505374 | HCID 178505374 | — |
| 生成物 | HCID 22663744 | HCID 22663744 | — |
反応手順
A solution of 6-fluoro-2,2-dimethyl-chroman-4-one (EP 193493; 1 equiv.) in ethanol (0.24 M) was treated with copper chromite (0.6 equiv.). The reaction was heated to 200° C. for 6 hours at 3000 psi of hydrogen gas. The reaction was filtered and concentrated to a solid. The crude material was recrystallized form hot hexanes to give the title compound. MS found 198 [M+H]+
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06800651B2 |
| 出典データセット | uspto-grants-2004_10 |
| ORD ID | ord-53bacbbe0cda493bb6cdbae6e52d0284 |
| 出典メモ | uspto-grants-2004_10 |