Sulfuryl chloride → HCID 86762023、化合物

HRID 39247ノート

反応式

HRID 39247 の反応式
S(Cl)([Cl:4])(=O)=O.[C:6](=[O:35])([O:10][CH:11]([O:13][C:14](=[O:34])[CH2:15][CH2:16][CH:17]([P:26]([O:31][CH2:32][CH3:33])([O:28][CH2:29][CH3:30])=[O:27])[P:18]([O:23][CH2:24][CH3:25])([O:20][CH2:21][CH3:22])=[O:19])[CH3:12])SCC>C(Cl)Cl>[CH2:21]([O:20][P:18]([CH:17]([P:26]([O:31][CH2:32][CH3:33])([O:28][CH2:29][CH3:30])=[O:27])[CH2:16][CH2:15][C:14]([O:13][CH:11]([O:10][C:6]([Cl:4])=[O:35])[CH3:12])=[O:34])([O:23][CH2:24][CH3:25])=[O:19])[CH3:22]

参加物

4

反応物 2

HCID 24648Sulfuryl chlorideHCID 86762024S-Ethyl O-1-(4,4-bis(diethylphosphono)butanoyloxy)ethyl carbonothioate

生成物 1

HCID 86762023HCID 86762023、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

反応条件

温度
0 °C

実験手順

Sulfuryl chloride (78 μL, 0.96 mmol) was added drop-wise to a solution of 23 (237 mg, 0.48 mmol) in 10 mL of CH2Cl2 cooled to 0° C. The solution was stirred for 2 h. The solvent was removed under reduced pressure to afford chloroformate 24 and which was used for the next reaction without further purification.

後処理

  1. customThe solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-6e28a8d386fe456a9190bdf5a12e38f0
出典データセット
uspto-grants-2013_09
特許番号
US08524691B2

反応ノート

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