3-(3,4-Dimethoxyphenyl)-2-propenal → (E,E)-2-(Phenylethylaminocarbonyl)-3-(3,4-dimethoxystyryl)acrylonitrile

HRID 392477

反応式

HRID 392477 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[O:13][CH3:14])[CH:6]=[CH:7][CH:8]=O.[C:15]([CH2:17][C:18]([N-:20][CH2:21][CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)=[O:19])#[N:16]>>[C:23]1([CH2:22][CH2:21][NH:20][C:18](/[C:17](=[CH:8]/[CH:7]=[CH:6]/[C:5]2[CH:10]=[CH:11][C:12]([O:13][CH3:14])=[C:3]([O:2][CH3:1])[CH:4]=2)/[C:15]#[N:16])=[O:19])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

参加物

3

反応物 2

HCID 1075573-(3,4-Dimethoxyphenyl)-2-propenalHCID 178511181HCID 178511181、化合物

生成物 1

HCID 10109276(E,E)-2-(Phenylethylaminocarbonyl)-3-(3,4-dimethoxystyryl)acrylonitrile

実験手順

The compound was prepared as described in Example 3 by adding 3,4-dimethoxycinnamaldehyde (Example 6, 0.1 g, 0.52 mmol) to N-(cyanoacetyl)phenylethylamide (Example 20, 0.1 g, 0.52 mmol). After refluxing for 1 h and recrystallization from ethanol a yellow solid was obtained (0.12 g, 63%). The product gave the following analytical data:

後処理

  1. customThe compound was prepared
  2. temperatureAfter refluxing for 1 h
  3. customrecrystallization from ethanol a yellow solid
  4. customwas obtained (0.12 g, 63%)
  5. customThe product gave the following analytical data

出典と根拠

ORDレコード
ord-3c2519fed33b4ecba3aefc797ac7d1b3
出典データセット
uspto-grants-2004_10
特許番号
US06800659B2

関連ノート

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