化工社化工社 化学情報印刷レポート · 研究参考用
Piperidine → Phe-Gly
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | Fmoc-Phe-Gly-OH | HCID 11328236 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Phe-Gly | HCID 6992304 | — |
反応手順
Fmoc-protected dipeptide 72 (500 mg, 1.00 mmol) was treated with a 5% v/v solution of piperidine in DMF (5 mL). After stirring for 1 h, the reaction mixture was concentrated to dryness. The crude material was used for the next step without purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08524691B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-f2ae1b8090a940d2913985de4b8df854 |
| 出典メモ | uspto-grants-2013_09 |