化工社化工社 化学情報印刷レポート · 研究参考用
Piperidine → Glycyl-phenylalanyl-glycine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | N-Fmoc-glycyl-L-phenylalanyl-glycine | HCID 15222489 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Glycyl-phenylalanyl-glycine | HCID 6992441 | — |
反応手順
Fmoc-protected tripeptide 74 (546 mg, 0.98 mmol) was treated with a 5% v/v solution of piperidine in DMF (5 mL). After stirring for 45 min, the reaction mixture was concentrated to dryness. The crude material was used for the next step without purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08524691B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-7e66b13904154ebcbe524b75757fe2f1 |
| 出典メモ | uspto-grants-2013_09 |