化工社化工社 化学情報印刷レポート · 研究参考用
(4-Nitrophenyl)acetic acid → Benzeneacetyl chloride, 4-nitro-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4-Nitrophenyl)acetic acid | HCID 4661 | — |
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Benzeneacetyl chloride, 4-nitro- | HCID 6452210 | — |
反応手順
3.75 ml (7.5 mmoles) of a 2M solution of oxalyl chloride in dichloromethane is added at 20° C. to a solution of 0.9 g (5 mmoles) of 4-nitrophenylacetic acid in a mixture composed of 10 ml of dichloromethane and 0.5 ml of DMF. After agitation for 30 minutes, the solution is concentrated under vacuum. The yellow oil obtained is used without additional purification in the following stage.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06809088B2 |
| 出典データセット | uspto-grants-2004_10 |
| ORD ID | ord-a2c4d1ad5c0049ed90be11c40f056869 |
| 出典メモ | uspto-grants-2004_10 |