化工社化工社 化学情報印刷レポート · 研究参考用
Methyl 4-chlorobenzoate → Lithium 4-chlorobenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 4-chlorobenzoate | HCID 14307 | — |
| 反応物 | Lithium trimethylsilanolate | HCID 74821 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Lithium 4-chlorobenzoate | HCID 19205643 | 46.4% |
反応手順
The procedure of Example 1 was followed using methyl 4-chlorobenzoate (4.3 g, 25.2 mmol), lithium trimethylsilanolate (2.42 g, 25.2 mmol), and dry toluene (100 mL) and overnight heating at reflux. Lithium 4-chlorobenzoate (1.9 g, 46% yield) was isolated as a white solid: 1H NMR (D2O) δ 7.4 (ABq, Δν1-3 =31 Hz, J=9 Hz, Ar--H's, 2 H). This solid was contaminated with a small amount of lithium trimethylsilanolate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04723016 |
| 出典データセット | uspto-grants-1988_02 |
| ORD ID | ord-6e6d66be1f8a416f914ae00c5029e6a2 |
| 出典メモ | uspto-grants-1988_02 |