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HRID 394236作成日：2026年10月26日

Lithium Hydroxide → [Rac]-2-ethoxy-3-[2-methyl-4-[2-(5-methyl-2-phenyl-thiazol-4-yl)-ethoxy]-phenyl}-propionic acid

https://huagongshe.com/reaction/394236

反応式

関与物質

役割名称HCID仕込み量
反応物Lithium HydroxideHCID 3939—
反応物[Rac]-2-ethoxy-3-{2-methyl-4-[2-(5-methyl-2-phenyl-thiazol-4-yl)-ethoxy]-phenyl]-propionic acid ethyl esterHCID 68616609—
生成物[Rac]-2-ethoxy-3-[2-methyl-4-[2-(5-methyl-2-phenyl-thiazol-4-yl)-ethoxy]-phenyl}-propionic acidHCID 10002540—

反応手順

In analogy to the procedure described in example 10 d], [rac]-2-ethoxy-3-{2-methyl-4-[2-(5-methyl-2-phenyl-thiazol-4-yl)-ethoxy]-phenyl}-propionic acid ethyl ester was treated with LiOH to obtain [rac]-2-ethoxy-3-{2-methyl-4-[2-(5-methyl-2-phenyl-thiazol-4-yl)-ethoxy]-phenyl}-propionic acid as colorless solid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06809110B2
出典データセットuspto-grants-2004_10
ORD IDord-c20222cf626d456293cfc0de59de40f0
出典メモuspto-grants-2004_10