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HRID 394248作成日：2026年10月26日

Lithium Hydroxide → [Rac]-2-ethoxy-3-{4-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-propionic acid

https://huagongshe.com/reaction/394248

反応式

関与物質

役割名称HCID仕込み量
反応物Lithium HydroxideHCID 3939—
反応物[Rac]-2-ethoxy-3-{4-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-propionic acid ethyl esterHCID 68616772—
生成物[Rac]-2-ethoxy-3-{4-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-propionic acidHCID 22647562—

反応手順

In analogy to the procedure described in example 10 d], [rac]-2-ethoxy-3-{4-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-propionic acid ethyl ester was treated with LiOH to obtain [rac]-2-ethoxy-3-{4-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-propionic acid as colorless oil.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06809110B2
出典データセットuspto-grants-2004_10
ORD IDord-8c11c4ba38ea4dd2b1acddf854954dc0
出典メモuspto-grants-2004_10