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HRID 394283作成日：2026年10月26日

Lithium Hydroxide → [Rac]-3-{4-[2-(2-chloro-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid

https://huagongshe.com/reaction/394283

反応式

関与物質

役割名称HCID仕込み量
反応物Lithium HydroxideHCID 3939—
反応物[Rac]-3-{4-[2-(2-chloro-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid ethyl esterHCID 68616604—
生成物[Rac]-3-{4-[2-(2-chloro-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acidHCID 22647474—

反応手順

In analogy to the procedure described in example 10 d], [rac]-3-{4-[2-(2-chloro-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid ethyl ester was treated with LiOH to obtain [rac]-3-{4-[2-(2-chloro-phenyl)-thiazol-4-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid as colorless solid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06809110B2
出典データセットuspto-grants-2004_10
ORD IDord-08f88c6b710e42a69065629088637ebe
出典メモuspto-grants-2004_10