Lithium Hydroxide → HCID 22647413、化合物

HRID 394349

反応式

HRID 394349 の反応式
C([O:3][C:4](=[O:33])[CH:5]([O:30][CH2:31][CH3:32])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15]2[S:19][C:18]([C:20]3[CH:25]=[CH:24][C:23]([Cl:26])=[CH:22][C:21]=3[Cl:27])=[N:17][C:16]=2[CH3:28])=[CH:9][C:8]=1[CH3:29])C.[Li+].[OH-]>>[Cl:27][C:21]1[CH:22]=[C:23]([Cl:26])[CH:24]=[CH:25][C:20]=1[C:18]1[S:19][C:15]([CH2:14][O:13][C:10]2[CH:11]=[CH:12][C:7]([CH2:6][CH:5]([O:30][CH2:31][CH3:32])[C:4]([OH:33])=[O:3])=[C:8]([CH3:29])[CH:9]=2)=[C:16]([CH3:28])[N:17]=1

参加物

3

反応物 2

HCID 3939Lithium HydroxideHCID 68617601[Rac]-3-{4-[2-(2,4-dichloro-phenyl)-4-methyl-thiazol-5-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid ethyl ester

生成物 1

HCID 22647413HCID 22647413、化合物

実験手順

In analogy to the procedure described in example 10 d], [rac]-3-{4-[2-(2,4-dichloro-phenyl)-4-methyl-thiazol-5-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid ethyl ester was treated with LiOH to obtain [rac]-3-{4-[2-(2,4-dichloro-phenyl)-4-methyl-thiazol-5-ylmethoxy]-2-methyl-phenyl}-2-ethoxy-propionic acid as colorless solid.

後処理

  1. customdescribed in example 10 d

出典と根拠

ORDレコード
ord-9be98203287840fe9782d961294c7308
出典データセット
uspto-grants-2004_10
特許番号
US06809110B2

関連ノート

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