化工社化工社 化学情報印刷レポート · 研究参考用
Syringaldehyde → HCID 54431732、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Syringaldehyde | HCID 8655 | — |
| 反応物 | Ethyl Acetoacetate | HCID 8868 | — |
| 反応物 | Piperidin-1-yl-acetic acid | HCID 201097 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | HCID 54431732 | HCID 54431732 | — |
反応手順
Monodemethylation of 3,4,5-trimethoxy benzaldehyde using sulphuric acid at 40° C. for 8 hours as described above in Example 1 yields syringaldehyde. Condensation of 3,5-Dimethoxy-4-hydroxy benzaldehyde (syringaldehyde) with ethyl acetoacetate in the presence of piperidine—acetic acid and benzene as the reaction medium at reflux temperature yields the title product. The reaction takes about 3.5 hours for completion.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06602515B2 |
| 出典データセット | uspto-grants-2003_08 |
| ORD ID | ord-602d9d1954fa44eb829423fbca755f27 |
| 出典メモ | uspto-grants-2003_08 |