化工社化工社 化学情報印刷レポート · 研究参考用
N,N,N-trimethylglycinium → Methyl 3-[4-[(1,1-dimethylethoxy)]-4-oxo-3-[[(phenylmethoxy)-carbonyl]amino]butoxy]-benzenepropanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N,N,N-trimethylglycinium | HCID 248 | — |
| 反応物 | Methyl 3-(3-hydroxyphenyl)propionate | HCID 1512675 | — |
| 反応物 | AG-H-14083 | HCID 10804815 | — |
| 生成物 | Methyl 3-[4-[(1,1-dimethylethoxy)]-4-oxo-3-[[(phenylmethoxy)-carbonyl]amino]butoxy]-benzenepropanoate | HCID 18176951 | 67.9% |
反応手順
The operation is carried out as in Preparation 1 (Method 2) starting from 270 mg of the phenol prepared in Stage A, 309 mg of 1,1-dimethyl-ethyl N-[(phenylmethoxy)carbonyl]-L-homoserinate and 616 mg of betaine. 320 mg of expected product is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06602878B1 |
| 出典データセット | uspto-grants-2003_08 |
| ORD ID | ord-cedc6fdd6cc44c19875c49c35baec381 |
| 出典メモ | uspto-grants-2003_08 |