反応式
[F:1][C:2]1[CH:10]=[N:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[OH:11]O>C(O)(=O)C>[F:1][C:2]1[CH:10]=[N+:9]([O-:11])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]参加物
4
反応条件
- 温度
- 75 °C
実験手順
To a solution of 3-fluoroisonicotinic acid (5.0 g, 35.33 mmol) in acetic acid (25 ml) was added hydrogen peroxide (6 ml). The reaction mixture was stirred at 70-80° C. overnight. The solvent was removed to obtain 5.5 g of 3-fluoroisonicotinic acid 1-oxide in quantitative yield.
後処理
- customThe solvent was removed
出典と根拠
- ORDレコード
- ord-eefb4f777a6c4d60abf2477d1e1f9e78
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08524911B2
関連ノート
読み込み中…