Ethyl 2-bromobenzoate → Ethyl 3',4',5'-trimethoxy[1,1'-biphenyl]-2-carboxylate

HRID 395460

反応式

HRID 395460 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5](B(O)O)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].Br[C:17]1[CH:27]=[CH:26][CH:25]=[CH:24][C:18]=1[C:19]([O:21][CH2:22][CH3:23])=[O:20]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:24]2[CH:25]=[CH:26][CH:27]=[CH:17][C:18]=2[C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10]

参加物

3

反応物 2

HCID 80186Ethyl 2-bromobenzoateHCID 27343903,4,5-Trimethoxybenzeneboronic acid

生成物 1

HCID 22558004Ethyl 3',4',5'-trimethoxy[1,1'-biphenyl]-2-carboxylate

実験手順

3,4,5-Trimethoxyphenylboronic acid (639 mg) and ethyl 2-bromobenzoate (479 mg) were condensed in the same manner as described in Preparation Example 1 to give the title compound.

後処理

  1. customcondensed in the same manner
  2. customas described in Preparation Example 1

出典と根拠

ORDレコード
ord-7fa35a672f80465bb7ea0a5d7e4038dc
出典データセット
uspto-grants-2003_08
特許番号
US06605620B1

関連ノート

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