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4-(Aminomethyl)Benzoic Acid → 4-[({3-[(2-Fluoro-4-iodophenyl)amino]isonicotinoyl}amino)methyl]benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(Aminomethyl)Benzoic Acid | HCID 65526 | — |
| 反応物 | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| 生成物 | 4-[({3-[(2-Fluoro-4-iodophenyl)amino]isonicotinoyl}amino)methyl]benzoic acid | HCID 11720125 | — |
反応手順
4-[({3-[(2-fluoro-4-iodophenyl)amino]isonicotinoyl}amino)methyl]benzoic acid was synthesized according to the procedure for General Method 1, outlined above, starting with 0.3 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.45 mmol of 4-aminomethylbenzoic acid. LC/MS [9.25 min; 492 (M+1)]
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08524911B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-42ed145d36574f8f872f590873590c04 |
| 出典メモ | uspto-grants-2013_09 |