N-(2-aminoethyl)acetamide → N-(2-Acetylamino-ethyl)-3-(2-chloro-4-iodo-phenylamino)-isonicotinamide
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[CH:18]=[N:17][CH:16]=[CH:15][C:11]=1[C:12]([OH:14])=O.[NH2:19][CH2:20][CH2:21][NH:22][C:23](=[O:25])[CH3:24]>>[C:23]([NH:22][CH2:21][CH2:20][NH:19][C:12](=[O:14])[C:11]1[CH:15]=[CH:16][N:17]=[CH:18][C:10]=1[NH:9][C:3]1[CH:4]=[CH:5][C:6]([I:8])=[CH:7][C:2]=1[Cl:1])(=[O:25])[CH3:24]参加物
3
実験手順
N-(2-Acetylamino-ethyl)-3-(2-chloro-4-iodo-phenylamino)-isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.32 mmol of 3-[(2-chloro-4-iodophenyl)amino]isonicotinic acid (intermediate 2) and 0.44 mmol N-(2-amino-ethyl)-acetamide LC/MS [8.38 min; 4.59 (M+1)]
出典と根拠
- ORDレコード
- ord-1b56b321044c4eb28ead92f30db47523
- 出典データセット
- uspto-grants-2013_09