化工社化工社 化学情報印刷レポート · 研究参考用
Acetyl chloride → Ethanone, 1-(4-octylphenyl)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetyl chloride | HCID 6367 | — |
| 反応物 | Octylbenzene | HCID 16607 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | 1,1-Dichloroethane | HCID 6365 | — |
| 生成物 | Ethanone, 1-(4-octylphenyl)- | HCID 66344 | — |
反応手順
Aluminum chloride (22.6 g) is suspended in dichloroethane (500 ml) and octylbenzene (16) (21.5 g) is added at room temperature. To the mixture is added acetyl chloride (8.87 g) under ice-cooling. The mixture is stirred at room temperature overnight. The reaction mixture is poured into ice water and extracted with ether. The organic layer is washed with brine and dried over sodium sulfate. The solvent is evaporated to give 4′-octylacetophenone (18′) as a colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06605744B2 |
| 出典データセット | uspto-grants-2003_08 |
| ORD ID | ord-f0335febdb6e4fc9a41e2e6dafd45797 |
| 出典メモ | uspto-grants-2003_08 |