Propanoic acid, 2,2,3,3,3-pentafluoro-, methyl ester → Sodium pentafluoropropionate

HRID 3964

反応式

HRID 3964 の反応式
[F:1][C:2]([F:11])([C:7]([F:10])([F:9])[F:8])[C:3]([O:5]C)=[O:4].C[Si](C)(C)[O-].[Na+:17]>C(Cl)Cl>[F:1][C:2]([F:11])([C:7]([F:10])([F:9])[F:8])[C:3]([O-:5])=[O:4].[Na+:17]

参加物

4

反応物 2

HCID 9783Propanoic acid, 2,2,3,3,3-pentafluoro-, methyl esterHCID 23672319Sodium trimethylsilanolate

生成物 1

HCID 2733305Sodium pentafluoropropionate収率 92%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

The procedure of Example 1 was followed using methyl perfluoropropionate (3 mL, 23.4 mmol), sodium trimethylsilanolate (2.63 g, 23.4 mmol), dry methylene chloride (100 mL), and a 1 h reaction time. Sodium perfluoropropionate (4.0 g, 92% yield) was obtained as a white solid: 1H NMR (D2O) δ -82.4 (t, J=2 Hz, CF3, 3F), -120.1 ppm (q, J=2 Hz, CF2, 2F).

後処理

  1. customa 1 h reaction time

出典と根拠

ORDレコード
ord-f50e1f0a36124d9191e96386a1984340
出典データセット
uspto-grants-1988_02
特許番号
US04723016

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