関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Succinimide | HCID 11439 | — |
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 反応物 | Methyl 3-methoxy-2-o-tolylacrylate | HCID 435882 | — |
| 触媒 | Azobisisobutyronitrile | HCID 6547 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | Methyl 2-[2-(bromomethyl)phenyl]-3-methoxyprop-2-enoate | HCID 53395349 | 97.3% |
反応手順
20.6 g of the methyl α-(2-methylphenyl)-β-methoxyacrylate obtained as described in method A, 17.65 g of N-bromosuccinimide, 0.2 g of azobisisobutyronitrile and 150 ml of CCl4 are slowly heated to 90° C. and kept at this temperature until all of the succinimide floats on the solvent. The mixture is filtered, the filtrate is evaporated down, and the oil which remains is dissolved in about 5 ml of acetone and brought to crystallization with n-hexane. 27.5 g of colorless crystals of melting point 86°-87° C. are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04723034 |
|---|
| 出典データセット | uspto-grants-1988_02 |
|---|
| ORD ID | ord-f360e909fa154e73a99b18eae08d738d |
|---|
| 出典メモ | uspto-grants-1988_02 |
|---|
