化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → isobutyl (S)-2-(6-methoxy-2-naphthyl)propionate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Naproxen | HCID 156391 | — |
| 溶媒 | Isobutanol | HCID 6560 | — |
| 生成物 | isobutyl (S)-2-(6-methoxy-2-naphthyl)propionate | HCID 54469957 | — |
反応手順
A solution of 300 mg of (S)-2-(6-methoxy-2-naphthyl)propionic acid in 5 ml of isobutyl alcohol is saturated with hydrogen chloride. After 24 hours, the excess alcohol is distilled off in vacuo and the residue is purified by chromatography using an alumina substrate to yield isobutyl (S)-2-(6-methoxy-2-naphthyl)propionate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04723033 |
| 出典データセット | uspto-grants-1988_02 |
| ORD ID | ord-8b2fe1a99b9b4f7d9bf65ad29d804e7a |
| 出典メモ | uspto-grants-1988_02 |