化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → HCID 23445018、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Ethyl orthoformate | HCID 31214 | — |
| 反応物 | Ethyl nitroacetate | HCID 69379 | — |
| 反応物 | 3-Amino-5-fluorobenzotrifluoride | HCID 2735913 | — |
| 触媒 | Iron | HCID 23925 | — |
| 生成物 | HCID 23445018 | HCID 23445018 | — |
反応手順
Following the general method described in example 234, 3-fluoro-5-trifluoromethylaniline was reacted with triethyl orthoformate, ethyl nitroacetate and acetic acid followed by treatment with triethyl orthoformate, iron and acetic acid and subsequent alkaline hydrolysis. The title compound was obtained as a white crystalline solid. Mp.>250° C. (H2O/dioxane), MS: m/e=273 (M−H−).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06610723B2 |
| 出典データセット | uspto-grants-2003_08 |
| ORD ID | ord-b147aa1cff6e43aeaab32b572cddd72d |
| 出典メモ | uspto-grants-2003_08 |