HCID 23000218、化合物 → HCID 23000253、化合物
反応式
[C:1]([N:4]([C:10]1[N:15]=[CH:14][CH:13]=CN=1)[CH2:5][CH2:6][CH2:7][C:8]#[CH:9])(=[O:3])[CH3:2]>[N+](C1C=CC=CC=1)([O-])=O>[C:1]([N:4]1[C:10]2[C:7](=[C:8]([CH3:9])[CH:13]=[CH:14][N:15]=2)[CH2:6][CH2:5]1)(=[O:3])[CH3:2]参加物
3
実験手順
A solution of 2-(N-acetyl-N-pent-4-ynylamino)pyrimidine (3.49 g, 17.2 mmol) in nitrobenzene (35 mL) was heated under argon at 180° C. for 2 days. The reaction mixture was cooled and loaded directly onto a dry silica get column. The column was first eluted with methylene chloride to wash off the nitrobenzene and then was eluted with ether to give after evaporation in vacuo to give the title compound as a pale yellow solid:
後処理
- temperatureThe reaction mixture was cooled
- customget column
- washThe column was first eluted with methylene chloride
- washto wash off the nitrobenzene
- washwas eluted with ether
- customto give
- customafter evaporation in vacuo
出典と根拠
- ORDレコード
- ord-4660dcf9e4ad498fa43053eaf3ddf8ee
- 出典データセット
- uspto-grants-2003_08
- 特許番号
- US06610692B1
反応ノート
読み込み中…