関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | 2-Chloropyridine-3,5-dicarbonitrile | HCID 10986579 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 3-amino-1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile | HCID 178510334 | — |
反応手順
Hydrazine hydrate (55%, 125 mL, 2.20 mmol) was added to a stirred suspension of 2-chloro-3,5-dicyanopyridine (240 mg, 1.47 mmol) and triethylamine (205 μL, 1.47 mmol) in ethanol (3 mL) and the resulting red mixture was heated to 60° C. After 16 h the mixture was cooled and filtered to give the title compound:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06610692B1 |
|---|
| 出典データセット | uspto-grants-2003_08 |
|---|
| ORD ID | ord-fb4f728e33fb4941921077b54130ea1b |
|---|
| 出典メモ | uspto-grants-2003_08 |
|---|
