3-Chloro-4-phenoxyaniline → 4-(3-Chloro-4-phenoxyanilino)-6,7-dimethoxyquinazoline hydrochloride salt

関与物質

反応手順

Using an analogous procedure to that described in Example 1 except that the reaction mixture was heated to reflux for 16 hours, 4-amino-2-chlorophenyl phenyl ether was reacted with 4-chloro-6,7-dimethoxyquinazoline hydrochloride to give 4-(3-chloro-4-phenoxyanilino)-6,7-dimethoxyquinazoline hydrochloride salt in 56% Yield, m.p. 260°-265° C.;

情報源と証拠