2-Chloro-1-fluoro-4-nitrobenzene → 3-Chloro-4-(2-thiazolylthio)nitrobenzene
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[CH:5]=[CH:6][C:7]=1F.[S:12]1[CH:16]=[CH:15][N:14]=[C:13]1[SH:17]>>[S:12]1[CH:16]=[CH:15][N:14]=[C:13]1[S:17][C:7]1[CH:6]=[CH:5][C:4]([N+:9]([O-:11])=[O:10])=[CH:3][C:2]=1[Cl:1]参加物
3
実験手順
Using an analogous procedure to that described in the first paragraph of the portion of Example 8 which is concerned with the preparation of starting materials, 3-chloro-4-fluoronitrobenzene was reacted with 2-thiazolethiol to give a precipitated solid which was partitioned between ethyl acetate and water. The organic phase was dried (MgSO4) and evaporated to give 2-chloro-4-nitrophenyl 2-thiazolyl sulphide in 26% yield.
後処理
- customto give a precipitated solid which
- customwas partitioned between ethyl acetate and water
- dry with materialThe organic phase was dried (MgSO4)
- customevaporated
出典と根拠
- ORDレコード
- ord-ef581cff486446fe8604b1eb80db8312
- 出典データセット
- uspto-grants-1998_10
- 特許番号
- US05821246
反応ノート
読み込み中…