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4,7-Dichloro-6-nitroquinazoline → 7-Chloro-4-[3-methyl-4-(2-pyridylmethoxy)anilino]-6-nitroquinazoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4,7-Dichloro-6-nitroquinazoline | HCID 10490455 | — |
| 反応物 | 3-Methyl-4-(pyridin-2-ylmethoxy)aniline | HCID 23438288 | — |
| 生成物 | 7-Chloro-4-[3-methyl-4-(2-pyridylmethoxy)anilino]-6-nitroquinazoline | HCID 18967569 | 81% |
反応手順
Using an analogous procedure to that described in Example 1, 4,7-dichloro-6-nitroquinazoline was reacted with 5-amino-2-tolyl 2-pyridylmethyl ether to give 7-chloro-4-[3-methyl-4-(2-pyridylmethoxy)anilino]-6-nitroquinazoline in 81% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05821246 |
| 出典データセット | uspto-grants-1998_10 |
| ORD ID | ord-a2a4ef68da1048fba24fa83088329ecc |
| 出典メモ | uspto-grants-1998_10 |