化工社化工社 化学情報印刷レポート · 研究参考用
(+-)-Pantolactone → Keto-pantoyllactone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (+-)-Pantolactone | HCID 989 | — |
| 反応物 | Trichloroisocyanuric Acid | HCID 6909 | — |
| 触媒 | Tempo | HCID 2724126 | — |
| 生成物 | Keto-pantoyllactone | HCID 39 | 93.5% |
反応手順
5 g (38.4 mmol) of pantolactone were reacted with 3.6 g (15.5 mmol) of trichloroisocyanuric acid as described in Example 13. In contrast to Example 13, 60 mg (0.25 mmol) of TEMPO derivative C were used as the catalyst. The reaction had finished after 3 hours. After recrystallization of the crude product there were obtained 4.6 g (93%) of ketopantolactone, m.p. 69°-70° C., GC content: 100% (area percent).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05821374 |
| 出典データセット | uspto-grants-1998_10 |
| ORD ID | ord-05d2bc7a176a47628cfe714f094b364a |
| 出典メモ | uspto-grants-1998_10 |