Piperazine → HCID 131718840、化合物

HRID 399733

反応式

HRID 399733 の反応式
[C:1]([NH:4][C@H:5]([C:18]([OH:20])=[O:19])[CH2:6][S:7][S:8][CH2:9][C@H:10]([NH:14][C:15](=[O:17])[CH3:16])[C:11]([OH:13])=[O:12])(=[O:3])[CH3:2].[NH:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>O>[NH2+:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1.[C:15]([NH:14][C@H:10]([C:11]([O-:13])=[O:12])[CH2:9][S:8][S:7][CH2:6][C@H:5]([NH:4][C:1](=[O:3])[CH3:2])[C:18]([O-:20])=[O:19])(=[O:17])[CH3:16]

参加物

4

反応物 2

HCID 4837PiperazineHCID 6995101N,N'-Diacetyl-L-cystine

生成物 1

HCID 131718840HCID 131718840、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To N,N'-diacetyl-L-cystine (4.60 mmole, 1.49 g) dissolved in 5 mL of water was added piperazine (4.60 mmole, 0.90 g). To the solution was added enough isopropanole to cause formation of an oil, which slowly solidifies. The salt was isolated and dried. Physical data: Mp >170° C. (dec.) 1H-NMR (D2O) δ: 2.05 [6H,s,CH3 ], 2.96 [2H,dd,CH2S], 3.26 [2H,dd,CH2S], 3.42 [8H,s,CH2 (2,3,5,6)], 4.49 [2H,dd,CHN]

後処理

  1. additionTo the solution was added enough isopropanole
  2. customThe salt was isolated
  3. customdried

出典と根拠

ORDレコード
ord-d8e32015c1a74521bdc6954b216fce32
出典データセット
uspto-grants-1998_10
特許番号
US05824681

関連ノート

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