HCID 18945167、化合物 → Methyl 3-formyl-5-(1H-pyrrol-1-yl)benzoate
反応式
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([N:13]2[CH:17]=[CH:16][CH:15]=[CH:14]2)[CH:12]=1)[C:6]([O:8][CH3:9])=[O:7]>ClCCl.[O-2].[O-2].[Mn+4]>[CH:2]([C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([N:13]2[CH:17]=[CH:16][CH:15]=[CH:14]2)[CH:12]=1)[C:6]([O:8][CH3:9])=[O:7])=[O:1]参加物
4
実験手順
A mixture of methyl 3-hydroxymethyl-5-(pyrrol-1-yl)benzoate (20.0 g) and manganese dioxide (100.0 g) in dichloromethane (0.5 l) was stirred for 22 hours at room temperature. The manganese dioxide was filtered off and the filtrate was evaporated in vacuo. The residue was pulverized from diisopropyl ether and petroleum ether to give methyl 3-formyl-5-(pyrrol-1-yl)benzoate (17.6 g).
後処理
- filtrationThe manganese dioxide was filtered off
- customthe filtrate was evaporated in vacuo
出典と根拠
- ORDレコード
- ord-5f260cc589b34e5eab58c04327dab822
- 出典データセット
- uspto-grants-1998_10
- 特許番号
- US05824691
反応ノート
読み込み中…