Fumaric Acid → 2-[3-(2-Cyanopyrrol-1-yl)benzoyl]guanidine fumarate
反応式
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[C:9]([C:11]1[N:12]([C:16]2[CH:17]=[C:18]([CH:25]=[CH:26][CH:27]=2)[C:19]([N:21]=[C:22]([NH2:24])[NH2:23])=[O:20])[CH:13]=[CH:14][CH:15]=1)#[N:10]>CO>[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[C:9]([C:11]1[N:12]([C:16]2[CH:17]=[C:18]([CH:25]=[CH:26][CH:27]=2)[C:19]([N:21]=[C:22]([NH2:23])[NH2:24])=[O:20])[CH:13]=[CH:14][CH:15]=1)#[N:10]参加物
4
実験手順
A solution of fumaric acid (0.46 g) in methanol (10 ml) was added to a solution of 2-[3-(2-cyanopyrrol-1-yl)benzoyl]guanidine (1.0 g) in methanol (10 ml) and the whole was stirred for 1 hour at ambient temperature. The isolated precipitate was collected by filtration and the precipitate was recrystallized from methanol-water to give 2-[3-(2-cyanopyrrol-1-yl)benzoyl]guanidine fumarate (1.03 g).