Methyl Acrylate → Methyl 3-(benzyl(methyl)amino)propanoate

HRID 400208ノート

反応式

HRID 400208 の反応式
[CH3:1][NH:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[C:10]([O:14][CH3:15])(=[O:13])[CH:11]=[CH2:12]>CO>[CH3:1][N:2]([CH2:12][CH2:11][C:10]([O:14][CH3:15])=[O:13])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

参加物

4

反応物 2

HCID 7294Methyl AcrylateHCID 7669N-Methylbenzylamine

生成物 1

HCID 824679Methyl 3-(benzyl(methyl)amino)propanoate収率 100%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A! Using N-methylbenzylamine (53 ml, 0.41 mole) and methyl acrilate (184 ml, 2.05 mole) in 430 ml of methanol, according to the procedure of Example 15,A!, there were obtained 85 g (quantitative yield) of methyl 3-(N-methyl-N-benzylamino)propanoate which was used as such in the next step.

出典と根拠

ORDレコード
ord-325edf8e2b1c48c9b81403a97f76deaf
出典データセット
uspto-grants-1998_10
特許番号
US05827881

反応ノート

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