Methyl Acrylate → HCID 11636953、化合物
反応式
[C:1]([O:5][CH3:6])(=[O:4])[CH:2]=[CH2:3].[CH:7]([NH:10][CH:11]([CH3:13])[CH3:12])([CH3:9])[CH3:8]>CO>[CH:7]([N:10]([CH2:3][CH2:2][C:1]([O:5][CH3:6])=[O:4])[CH:11]([CH3:13])[CH3:12])([CH3:9])[CH3:8]参加物
4
実験手順
A! Methyl acrilate (89 ml, 0.988 mmole) was slowly dropped into a solution of diisopropylamine (27.7 ml, 0.198 mmole) in methanol (300 ml) at -10° C. The reaction mixture was brought to room temperature and stirred for 24 hours, then the solvent and the methyl acrilate in excess were evaporated off thus obtaining 37 g of crude methyl 3-(N,N-diisopropylamino)propionate (quantitative yield) which was directly employed in the next step.
後処理
- customwas brought to room temperature
- customthe solvent and the methyl acrilate in excess were evaporated off
出典と根拠
- ORDレコード
- ord-95549129f5c94095b747003632130b96
- 出典データセット
- uspto-grants-1998_10
- 特許番号
- US05827881
反応ノート
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