5-Methylnicotinic acid → (4-Iodo-5-methyl-pyridin-3-yl)-carbamic acid tert-butyl ester

反応式

[CH3:1]C1C=NC=C(C=1)C(O)=O.[C:11]([O:15][C:16](=[O:29])[NH:17][C:18]1[CH:19]=[N:20][C:21](C(F)(F)F)=[CH:22][C:23]=1[I:24])([CH3:14])([CH3:13])[CH3:12]>>[C:11]([O:15][C:16](=[O:29])[NH:17][C:18]1[CH:19]=[N:20][CH:21]=[C:22]([CH3:1])[C:23]=1[I:24])([CH3:12])([CH3:13])[CH3:14]

参加物

反応物 2

HCID 2562085-Methylnicotinic acid

HCID 60026433(4-Iodo-6-trifluoromethylpyridin-3-yl)carbamic acid tert-butyl ester

生成物 1

HCID 60026355(4-Iodo-5-methyl-pyridin-3-yl)-carbamic acid tert-butyl ester

実験手順

The title product was prepared from 5-methylnicotinic acid in the same manner as in the preparation of (4-iodo-6-trifluoromethylpyridin-3-yl)carbamic acid tert-butyl ester.

出典と根拠

ORDレコード: ord-38c2a79929724efcab90240367c3c542
出典データセット: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08741897B2

反応ノート

読み込み中…