化工社化工社 化学情報印刷レポート · 研究参考用
2-Methoxy-3-nitropyridine → 3-Amino-2-methoxypyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methoxy-3-nitropyridine | HCID 253219 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3-Amino-2-methoxypyridine | HCID 2737488 | 87% |
反応手順
A solution of 2-methoxy-3-nitro-pyridine (70. g, 0.45 mol) in methanol (700 mL) containing palladium on carbon (7 g, 10%) was stirred under an atmosphere of hydrogen for 15 hours. The catalyst was filtered and washed with methanol. The filtrate was evaporated to dryness to give crude 2-methoxy-pyridin-3-ylamine (48 g, 0.39 mol, 87%), which was used directly in the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08741939B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-a4a258994c364f5d8376e8f8bf129688 |
| 出典メモ | uspto-grants-2014_06 |