2-(Chloromethyl)-1,3-oxazole → 2-Isopropyl-6-methoxy-1-(oxazol-2-ylmethyl)-1H-indole-3-carbaldehyde
反応式
[CH:1]([C:4]1[NH:5][C:6]2[C:11]([C:12]=1[CH:13]=[O:14])=[CH:10][CH:9]=[C:8]([O:15][CH3:16])[CH:7]=2)([CH3:3])[CH3:2].Cl[CH2:18][C:19]1[O:20][CH:21]=[CH:22][N:23]=1>>[CH:1]([C:4]1[N:5]([CH2:18][C:19]2[O:20][CH:21]=[CH:22][N:23]=2)[C:6]2[C:11]([C:12]=1[CH:13]=[O:14])=[CH:10][CH:9]=[C:8]([O:15][CH3:16])[CH:7]=2)([CH3:3])[CH3:2]参加物
3
実験手順
2-Isopropyl-6-methoxy-1H-indole-3-carbaldehyde (Compound 137, 0.54 g, 2.49 mmol) and 2-(chloromethyl)oxazole (0.58 g, 4.4 mmol) were reacted as described in General Procedure J to give the title compound as an oil.
出典と根拠
- ORDレコード
- ord-30bd3f1e317a4f9bb85a6f93a596445e
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08524917B2
反応ノート
読み込み中…