化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 4-([[3-Chloro-4-(trifluoromethyl)benzyl]amino]carbonyl)benzenesulfonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-Chloro-4-(trifluoromethyl)benzylamine | HCID 23512744 | — |
| 反応物 | Potassium 4-carboxybenzenesulfonate | HCID 23670833 | — |
| 生成物 | 4-([[3-Chloro-4-(trifluoromethyl)benzyl]amino]carbonyl)benzenesulfonyl chloride | HCID 57731928 | 45% |
反応手順
The title compound was prepared from 4-sulphobenzoic acid monopotassium salt and 3-chloro-4-(trifluoromethyl)benzylamine in 45% yield following the procedure described in Preparation 1. The thionyl chloride solution was heated at reflux for 3 hours.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08741934B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-744406d3034340fcb6671c74fe7e611b |
| 出典メモ | uspto-grants-2014_06 |