関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Phenylhydrazine hydrochloride | HCID 60962 | — |
| 反応物 | Ethyl 2,4,5-trifluorobenzoylacetate | HCID 2758933 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-phenyl-5-(2,4,5-trifluorophenyl)-2,4-dihydro-3H-pyrazol-3-one | HCID 66765091 | — |
反応手順
Potassium carbonate (153 mg, 1.10 mmol) was added to a stirred mixture of phenyl hydrazine HCl salt (160 mg, 1.10 mmol) and ethyl 3-oxo-3-(2,4,5-trifluorophenyl)propanoate (272 mg, 1.10 mmol) in EtOH (6 mL) and the mixture was heated at 70° C. for 1 hour. The solution was cooled to room temperature and was concentrated to give the title compound, which was taken on to the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08742110B2 |
|---|
| 出典データセット | uspto-grants-2014_06 |
|---|
| ORD ID | ord-3b8aeac09dcf44bfbc8b68645c6200f3 |
|---|
| 出典メモ | uspto-grants-2014_06 |
|---|
