Potassium Fluoride → 1-(Methoxymethyl)-1-methylpyrrolidin-1-ium fluoride

A 0.44 g quantity of potassium fluoride (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 11 g of deionized water, and 1.74 g of N-methoxymethyl-N-methylpyrrolidinium perchlorate was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. With addition of 100 ml of methanol, the reaction mixture was filtered. The filtrate was concentrated and dried in a vacuum. The residue was then dissolved in dichloromethane, the solution was again filtered with a membrane filter, and the filtrate was concentrated and dried, giving 1.05 g of the desired product.

1. customThe mixture was reacted at room temperature for 1.5 hours
2. customwhereby the reaction was terminated
3. additionWith addition of 100 ml of methanol
4. filtrationthe reaction mixture was filtered
5. concentrationThe filtrate was concentrated
6. customdried in a vacuum
7. dissolutionThe residue was then dissolved in dichloromethane
8. filtrationthe solution was again filtered with a membrane
9. filtrationfilter
10. concentrationthe filtrate was concentrated
11. customdried

ORDレコード

ord-fd0b341331664a4981901c7afb0777e3

出典データセット

uspto-grants-2014_06

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US08747690B2