Sodium Acetate → 1-(Methoxymethyl)-1-methylpyrrolidin-1-ium acetate
反応式
[C:1]([O-:4])(=[O:3])[CH3:2].[Na+].[Cl-].[CH3:7][N+:8]1([CH2:13][O:14][CH3:15])[CH2:12][CH2:11][CH2:10][CH2:9]1>CO>[C:1]([O-:4])(=[O:3])[CH3:2].[CH3:15][O:14][CH2:13][N+:8]1([CH3:7])[CH2:12][CH2:11][CH2:10][CH2:9]1参加物
4
実験手順
A 9.46 g quantity of sodium acetate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 95 g of methanol, and 19.10 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. The reaction mixture was filtered, and the filtrate was concentrated and dried in a vacuum. To the residue was added 100 ml of dichloromethane, followed by filtration with a membrane filter, concentration in a vacuum and drying, affording 20.38 g of the desired product.
後処理
- customThe mixture was reacted at room temperature for 1.5 hours
- customwhereby the reaction was terminated
- filtrationThe reaction mixture was filtered
- concentrationthe filtrate was concentrated
- customdried in a vacuum
- additionTo the residue was added 100 ml of dichloromethane
- filtrationfollowed by filtration with a membrane
- filtrationfilter
- concentrationconcentration in a vacuum
- customdrying
出典と根拠
- ORDレコード
- ord-ce52c98e76ab49fa8558cdc8cc323ae2
- 出典データセット
- uspto-grants-2014_06
- 特許番号
- US08747690B2
反応ノート
読み込み中…