1-(3-Fluoro-5-(3-methylisoxazol-5-yl)pyridin-2-yl)hydrazine → 4-((8-Fluoro-6-(3-methylisoxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methoxy)quinolin-7-ol
反応式
Br.[OH:2][C:3]1[CH:12]=[C:11]2[C:6]([C:7]([O:13][CH2:14][C:15](O)=O)=[CH:8][CH:9]=[N:10]2)=[CH:5][CH:4]=1.[F:18][C:19]1[C:20]([NH:31][NH2:32])=[N:21][CH:22]=[C:23]([C:25]2[O:29][N:28]=[C:27]([CH3:30])[CH:26]=2)[CH:24]=1>>[F:18][C:19]1[C:20]2[N:21]([C:15]([CH2:14][O:13][C:7]3[C:6]4[C:11](=[CH:12][C:3]([OH:2])=[CH:4][CH:5]=4)[N:10]=[CH:9][CH:8]=3)=[N:32][N:31]=2)[CH:22]=[C:23]([C:25]2[O:29][N:28]=[C:27]([CH3:30])[CH:26]=2)[CH:24]=1参加物
3
実験手順
The material was prepared using general method A (with 2-(7-hydroxyquinolin-4-yloxy)acetic acid hydrobromide and 1-(3-fluoro-5-(3-methylisoxazol-5-yl)pyridin-2-yl)hydrazine
後処理
- customThe material was prepared
出典と根拠
- ORDレコード
- ord-9e2ac0165b804ab1af0bed3ebb21f9cd
- 出典データセット
- uspto-grants-2013_09
- 特許番号
- US08524900B2
反応ノート
読み込み中…