関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethyl 2-thiopheneglyoxylate | HCID 77693 | — |
| 反応物 | 4,5-Dichloro-1,2-phenylenediamine | HCID 79297 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 6,7-dichloro-3-(thiophen-2-yl)quinoxalin-2(1H)-one | HCID 67289955 | — |
反応手順
A mixture of 4,5-dichlorobenzene-1,2-diamine (1.0 g, 5.65 mmol), ethyl 2-oxo-2-(thiophen-2-yl)acetate (1.056 g, 5.73 mmol) and ethanol (8 ml) was stirred at 70° C. for 11 h, cooled to room temperature, filtered and washed with cold ethanol. The collected pale yellow solid was dried further (1.07 g) and used directly in next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08748374B2 |
|---|
| 出典データセット | uspto-grants-2014_06 |
|---|
| ORD ID | ord-e2e509857fd348abbb23af2cdb1c66cc |
|---|
| 出典メモ | uspto-grants-2014_06 |
|---|
