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HRID 403732作成日:2026年10月26日

4-Phenoxyphenyl isocyanate → (S)-Methyl 3-methyl-2-(1-oxo-6-(4-(3-(4-phenoxyphenyl)ureido)phenyl)isoindolin-2-yl)butanoate

https://huagongshe.com/reaction/403732

反応式

関与物質

役割名称HCID仕込み量
反応物4-Phenoxyphenyl isocyanateHCID 2734896—
反応物(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
生成物(S)-Methyl 3-methyl-2-(1-oxo-6-(4-(3-(4-phenoxyphenyl)ureido)phenyl)isoindolin-2-yl)butanoateHCID 12357099598%

反応手順

The compound of example 49 was prepared analogous to compound of example 7 by reaction of compound of example 6 with 4-phenoxy phenyl isocyanate.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08748426B2
出典データセットuspto-grants-2014_06
ORD IDord-4d0c9c8a7c6a4f298b99217347d4c45e
出典メモuspto-grants-2014_06