(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-2-(6-(4-(2,4-Difluorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid

関与物質

役割	名称	HCID	仕込み量
反応物	(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid	HCID 53303631	—
反応物	(S)-Methyl 2-(6-(4-(2,4-difluorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate	HCID 53303632	—
生成物	(S)-2-(6-(4-(2,4-Difluorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid	HCID 67307333	84%

The compound of example 110 was prepared analogous to compound of example 98 by hydrolysis of compound of example 109.