化工社化工社 化学情報印刷レポート · 研究参考用
3-Methoxyphenyl isothiocyanate → (S)-Methyl 2-(5-(4-(3-(3-methoxyphenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Methoxyphenyl isothiocyanate | HCID 137832 | — |
| 反応物 | (S)-Methyl 2-(5-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731499 | — |
| 反応物 | (S)-Methyl 2-(5-(4-(3-(2-fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731509 | — |
| 生成物 | (S)-Methyl 2-(5-(4-(3-(3-methoxyphenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123917782 | — |
反応手順
The compound of example 278 was prepared analogous to compound of example 256 by reaction of compound of example 223 with 3-methoxyphenyl isothiocyanate. The compound of example 278 was used directly without isolation, for the preparation of compound of example 279.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08748426B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-d8e80cef67594a5ebd2a3e712e4d7df9 |
| 出典メモ | uspto-grants-2014_06 |