化工社化工社 化学情報印刷レポート · 研究参考用
4-Pentylbenzoyl chloride → Methyl 2-methyl-2-(1-oxo-6-(4-(4-pentylbenzamido)phenyl)isoindolin-2-yl)propanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Pentylbenzoyl chloride | HCID 170812 | — |
| 反応物 | Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-2-methylpropanoate | HCID 67307528 | — |
| 反応物 | (S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123625862 | — |
| 生成物 | Methyl 2-methyl-2-(1-oxo-6-(4-(4-pentylbenzamido)phenyl)isoindolin-2-yl)propanoate | HCID 67306977 | 93% |
反応手順
The compound of example 524 was prepared analogous to compound of example 97 by reaction of compound of example 515 with 4-(n-pentyl)-benzoyl chloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08748426B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-6051875c64624f378a0b1b19294d922d |
| 出典メモ | uspto-grants-2014_06 |