4-(Trifluoromethyl)benzoyl chloride → HCID 67307169、化合物
反応式
C(NC1C=CC(C2C=C3C(CN([C@@H](C(C)C)C(OC)=O)C3=O)=CC=2)=CC=1)(=O)C1C=CC=CC=1.[NH2:34][C:35]1[CH:40]=[CH:39][C:38]([C:41]2[CH:49]=[C:48]3[C:44]([CH2:45][N:46]([CH:51]4[CH2:56][CH2:55][CH2:54][CH:53]([C:57]([O:59][CH3:60])=[O:58])[CH2:52]4)[C:47]3=[O:50])=[CH:43][CH:42]=2)=[CH:37][CH:36]=1.[F:61][C:62]([F:73])([F:72])[C:63]1[CH:71]=[CH:70][C:66]([C:67](Cl)=[O:68])=[CH:65][CH:64]=1>>[O:50]=[C:47]1[C:48]2[C:44](=[CH:43][CH:42]=[C:41]([C:38]3[CH:37]=[CH:36][C:35]([NH:34][C:67](=[O:68])[C:66]4[CH:70]=[CH:71][C:63]([C:62]([F:61])([F:72])[F:73])=[CH:64][CH:65]=4)=[CH:40][CH:39]=3)[CH:49]=2)[CH2:45][N:46]1[CH:51]1[CH2:56][CH2:55][CH2:54][CH:53]([C:57]([O:59][CH3:60])=[O:58])[CH2:52]1参加物
4
実験手順
The compound of example 550 was prepared analogous to compound of example 97 by reaction of compound of example 543 with 4-trifluoromethyl benzoyl chloride.