化工社化工社 化学情報印刷レポート · 研究参考用
Methyl 1-aminocyclobutane-1-carboxylate hydrochloride → Methyl 1-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclobutanecarboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 1-aminocyclobutane-1-carboxylate hydrochloride | HCID 42614147 | — |
| 反応物 | Methyl 4-(bromomethyl)-4'-nitrobiphenyl-3-carboxylate | HCID 67306641 | — |
| 反応物 | (S)-Methyl 3-methyl-2-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)butanoate | HCID 131731440 | — |
| 生成物 | Methyl 1-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclobutanecarboxylate | HCID 67313692 | 71% |
反応手順
The compound of example 573 was prepared analogous to compound of example 5 by reaction of compound of example 4 with methyl 1-aminocyclobutanecarboxylate hydrochloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08748426B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-3299c086db7c4247a596710f1681fa26 |
| 出典メモ | uspto-grants-2014_06 |