(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → 1-(6-(4-(4-Chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclobutane carboxylic acid

関与物質

役割	名称	HCID	仕込み量
反応物	(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid	HCID 53303631	—
反応物	Methyl 1-(6-(4-(4-chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclobutane carboxylate	HCID 70975309	—
生成物	1-(6-(4-(4-Chlorobenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclobutane carboxylic acid	HCID 67306454	93%

The compound of example 578 was prepared analogous to compound of example 98 by hydrolysis of compound of example 577.